{"id":149,"date":"2013-04-30T15:12:15","date_gmt":"2013-04-30T13:12:15","guid":{"rendered":"http:\/\/www.labsrl.com\/en\/microflora-and-periodontal-disease\/"},"modified":"2017-10-17T21:49:50","modified_gmt":"2017-10-17T19:49:50","slug":"microflora-and-periodontal-disease","status":"publish","type":"post","link":"https:\/\/www.labsrl.com\/en\/microflora-and-periodontal-disease\/","title":{"rendered":"Microflora and periodontal disease"},"content":{"rendered":"<h3>Dental Research Journal<\/h3>\n<p><!--more--><\/p>\n<p>LUCA SCAPOLI<sup>1<\/sup>, AMBRA GIRARDI<sup>1<\/sup>, ANNALISA PALMIERI<sup>2<\/sup>, TIZIANO TESTORI<sup>3<\/sup>, FRANCESCO ZUFFETTI<sup>3<\/sup>, RICCARDO MONGUZZI<sup>4<\/sup>, DORINA LAURITANO<sup>5<\/sup>, FRANCESCO CARINCI<sup>2<\/sup><\/p>\n<p><i><sup>1<\/sup>Departments of Histology, Embryology and Applied Biology, Centre of Molecular Genetics, CARISBO Foundation, University of Bologna, Bologna,<br \/>\n<sup>2<\/sup>Department of Medical-Surgical Sciences of Communication and Behavior, Section of Maxillofacial and Plastic Surgery, University of Ferrara, Ferrara,<br \/>\n<sup>3<\/sup>Dentistry, Galeazzi Hospital, Milan, Italy,<br \/>\n<sup>4<\/sup>Private Practice, Dentist, Milan, Italy,<br \/>\n<sup>5<\/sup>Neurosciences and Biomedical Technologies, University Milano Bicocca, Italy<\/i><\/p>\n<h3>Abstract<\/h3>\n<p style=\"text-align: justify;\"><strong>Background:<\/strong><br \/>\nPeriodontitis is a disease that affects and destroys the tissues that support teeth. Tissue damage results from a prolonged inflammatory response to an ecological shift in the composition of subgingival biofilms. Three bacterial species that constitute the red complex group, Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola, are considered the main pathogens involved in periodontitis.<\/p>\n<p style=\"text-align: justify;\"><strong>Materials and Methods:<\/strong><br \/>\nIn the present study, a real\u2011time polymerase chain reaction bases assay was designed to detect and quantify red complex species, then used to investigate 307 periodontal pocket samples from 127 periodontitis patients and 180 controls.<\/p>\n<p style=\"text-align: justify;\"><strong>Results:<\/strong><br \/>\nSignificant higher prevalence of red complex species and increased amount of P. gingivalis and T. denticola were detected in periodontal pocket of periodontitis patients.<\/p>\n<p style=\"text-align: justify;\"><strong>Conclusions:<\/strong><br \/>Results demonstrated that the test is a valuable tool to improve diagnosis of periodontal disease.<\/p>\n<div class=\"box box0\"><a href=\"http:\/\/www.labsrl.com\/wp-content\/uploads\/2015\/09\/201211-Dental-Research-Journal-Microflora-and-periodontal-disease.pdf\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-153\" src=\"http:\/\/www.labsrl.com\/wp-content\/uploads\/2013\/04\/Adobe_Acrobat_PDF.png\" alt=\"Adobe_Acrobat_PDF\" width=\"49\" height=\"62\" style=\"margin-bottom:0;\" \/> <strong>Leggi tutto l&#8217;articolo in PDF<\/strong><\/a><\/div>\n<p><a href=\"http:\/\/drj.mui.ac.ir\/index.php\/drj\" target=\"_blank\">http:\/\/drj.mui.ac.ir\/index.php\/drj<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dental Research Journal<\/p>\n","protected":false},"author":2,"featured_media":142,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.9.1 - 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